Jarrow Formulas Biotin : the singular vitamin that is also known as vitamin H, the skin and hair vitamin.
B vitamins are know for their role in carbohydrate, lipid and protein metabolism and are actually catalysts for many processes in the body. Biotin is found in large quantities in liver, egg yolk, milk and yeast.
Biotin is water-soluble like its' other B-vitamin peers and required for many processes. Deficiency results in scaly skin, muscular pain, pallor, loss of appetite, nausea, fatigue and elevated cholesterol levels. Even though there are many dietary sources of biotin, adequate amounts or even optimal amounts are not always obtained from food alone.
In certain cases the food intake of these dietary sources are not at all adequate or sometimes a high intake of these dietary foods is undesireble from another health perspective like too much egg yolk or in case of a lactose intolerance when milk as a dietary source is unthinkable.
In such cases you need a well-dosed supplement like Biotin 5.
• the skin, hair and nail vitamin thanks to important role in keratine production
• gives a glossy but healthy shine to hair and nails
• nescessary in case of deficiency when certain foods are not tolerated
• important for healthy cholesterol levels
• helps to maintain a persons healthy appetite
In the US, biotin is classified as vitamin B7, but in the NLs it is B8 or vitamin H
Biotin is known by many names, including Cis-hexahydro-2-oxo- 1H-thieno[3,4-d]-imidazole-4-valeric acid, biotina, Coenzyme R, D-biotin, vitamin B7, vitamin H and W Factor. It is a water-soluble B vitamin typically found in liver, egg yolk, cereals, legumes, and nuts. It is essential for normal skin and hair growth, lipid metabolism, and energy production (ATP). Biotin supplementation is used for preventing and managing biotin deficiency associated with pregnancy, long-term parenteral nutrition, malnutrition, rapid weight loss, alcoholism, blood sugar imbalance, and multiple carboxylase deficiency. Biotin also commonly is taken orally for hair loss, brittle nails, and for other purposes. For support in blood sugar regulation, a specific combination providing 2 mg biotin plus 600 mcg chromium daily has been used in clinical trials.
Hair & Nails
Some of the more overt signs of biotin deficiency are hair loss and a scaly red rash around the eyes, nose and mouth. Less clearly a result of a deficiency state is nail quality. Three small trials have shown that biotin supplementation (2.5 mg/day for up to six months) in women with brittle fingernails leads to significant improvement. The study that used scanning electron microscopy to assess fingernail thickness and splitting found that after biotin supplementation, fingernail thickness increased by 25% and splitting decreased.
Mechanisms of Action
Biotin-containing enzymes are involved in pyruvate decarboxylase (glycolysis), gluconeogenesis, fatty acid synthesis, propionate metabolism, and the catabolism of leucine in mammals. Biotin deficiency is most common in people with congenital biotinidase deficiency, malabsorption (such as short-gut syndrome), pregnancy, alcoholism, and in people receiving long-term parenteral nutrition.
Chronic poor blood sugar regulation may produce a biotin-deficient state. A Japanese study found biotin levels were lower in patients with high blood sugar levels than healthy controls. In this same study, oral supplementation of 3 mg biotin three times daily for one month lowered fasting glucose levels by 45 percent in high blood sugar subjects for whom sulfonylureas were no longer effective; no effect was observed in subjects taking placebo.
Oral biotin is virtually completely absorbed even at high intake levels. About half of the oral intake of biotin is excreted within 24 hours. Biotin is recycled endogenously.
Safety, Adverse Reactions and Interactions
Biotin is well tolerated. Biotin in an amount of 10 mg per day has been taken without adverse effects. No biotin toxicity has been reported in individuals supplemented with as much as 200 mg orally or 20 mg intravenously per day. Carbamazepine (Carbatrol,Tegretol). Phenobarbital, Phenytoin (Dilantin), Primidone (Mysoline) and a number of other pharmaceuticals can reduce plasma biotin levels.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
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take 1 capsules with water or acidic fruit juice during breakfast and lunch or as directed by a qualified physician
contains per daily serving (1 capsule)
Biotin 5.000 mcg (1667 % RDI)
RDI = Recommended Daily Intake
active ingredient (biotin), fillers (rice flour, vegetable magnesium stearate), anticoagulant (silicon dioxide), capsule (hydroxypropylmethylcellulose)
keep dry and closed at normal room temperature between 15 - 22°C.
keep out of reach of young children
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish, mollusks)