Bone-Up Powder 396g - calcium (MCHA) , magnesium, silicium, vitamin C, D3,K2 (MK-7) | Jarrow Formulas
Jarrow Formulas Bone-Up Powder is a comprehensive multi-nutrient bone health formula. Bone-Up Powder utilizes the finest source of calcium available: Australian bovine bone ossein microcrystalline hydroxyapatite from chemical-free, range-grazed calves less than two years old (bones from veal calves are never used).
Bone-Up Powder also contains vitamin D3, vitamin K2 (as MK-7 from natural fermentation [a more bioavailable form of vitamin K]) and JarroSil Activated Silicon® (a highly-bioavailable form of silicon) to support the proper deposition of calcium and maintenance of bone health.
Potassium citrate, a systemic alkalizer, is also added for optimal osteo support.
who can benefit from Bone-Up Powder?
Many people are not meeting the current recommendations for adequate calcium intake via diet or with supplement use. Bone-Up Powder provides needed calcium, but also includes other essentials for proper calcium utilisation by the body.
In conjunction with regular, weight bearing exercise and a healthy diet calcium helps teen and young adult women build bone mass and maintain bone health, these women may reduce the risk of bone loss later in life.
what distinguishes Bone-Up Powder?
• complete multinutrient bone-health system
• ossein microcrystalline hydroxyapatite contains active bone-growth factors
• improves bone density when combined with regular weight bearing exercise and a healthy diet
• contains additional nutrients for healthy joints
• suitable for men and women of all ages, children and even pets
how do the active ingredients function in Bone-Up Powder?
• ossein micrcrystalline hydroxyapatite (MCHA) produces more prolonged calcium balance than soluble calcium salts. Ossein MCHA provides both the inorganic constituents found in human bone AND the organic bone-growth factors that stimulate bone osteoblast cells
• vitamin D3 converts to calcitrol, the active form of vitamin D3, in the kidneys. Calcitrol enhances calcium and phosphorous absorption and stimulates the synthesis of osteocalcin, an important structural protein in bone. Vitamin D3 is superior to vitamin D2 as it has been shown to raise blood levels 70% better than D2
• potassium helps neutralize acidic physiological pH, which can adversely affect bone health. In maintaining the acid-alkaline balance in our bodies, potassium helps avoid unhealthy levels of calcium excretion in the urine
• MK-7 (menaquinone-7), the more bioavailable form of vitamin K2, remains in circulation much longer than vitamin K1 and is responsible for the carboxylation of specific bone proteins needed for building bone. MK-7 also discourages unwanted calcium deposition in arteries
• boron is a trace mineral important in calcium and bone metabolism. Supplemental boron has been shown to reduce excretion of calcium, magnesium and phosphorus
• manganese, copper, and zinc are essential components of several enzymes involved in the formation of bone
Bone mass and hydroxyapatite
In 1982, an important calcium supplementation study was concluded and reported by the Dept. of Medicine and Radiology, Royal Free Hospital in London, England. Fifty-three post-menopausal women diagnosed to have seriously impaired calcium absorption and accelerated bone loss were separated into three groups and studied for over 14 months. At the conclusion of the study, only the women that received 1,000 mg of calcium from hydroxyapatite along with vitamin D showed a significant increase in bone thickness.
Hydroxyapatite produces more prolonged calcium balance than soluble calcium salts. It also allows the bone osteoblast cells to be more receptive to its components and to build bone tissue. Furthermore, hydroxyapatite provides both the organic and inorganic constituents found in human bone: hydroxyapatite microcrystals consist of calcium, phosphorous, oxygen, and hydrogen; the trace minerals zinc, strontium, silicon and iron; and proteins, amino acids and aminoglycans.
Bone consists of calcium and phosphorous crystals embedded in a framework of interlocking protein fibers. The protein fibers are made primarily of collagen. The mineral crystals give bone hardness, strength, and rigidity. Collagen fibers impart their quality of flexibility. Hydroxyapatite composes 67% of the weight of bone, and the collagenous fibers make up the remaining 33%.
The average adult has 1,000 -1,200 grams of calcium in the body. Bones are the body’s largest calcium storehouse and will release calcium into the bloodstream in order to ensure correct blood levels of calcium. Thus, blood calcium levels can be normal while bone loss can be considerable.
Between 2 - 4% of a person’s skeleton is remodeled every year. This means that calcium and other minerals leave the bone in a process called resorption and then must be “remodeled” or replaced. Whether due to poor nutrition or reduced hormone levels with the onset of aging, the loss of calcium and other minerals from the bone creates tiny holes that make bones weak and brittle, particularly if collagen is being lost.
It has been estimated that post-menopausal women lose 0.7% to 2% of their bone per year while men lose 0.5%-0.7%. Between 45 and 75 years of age, women lose 30% of their skeletal structure and men lose 15%.
It starts with the finest source of calcium available: Australian bovine bone hydroxyapatite from chemical-free, range-grazed calves less than two years old (bones from veal calves are never used). Skeletal health, however, requires more than calcium. Scientific evidence conclusively demonstrates the need for other nutrients like vitamin D3, vitamin K, potassium, magnesium, boron, and trace minerals such as zinc, copper, and manganese.
Who needs to supplement calcium?
Research has indicated that 85% of women over the age of 20 and at least 50% of men from age 35 consume less than the RDI for calcium. Caffeine, alcohol, sugar, chocolate, high protein diets and soda pops – particularly colas that are high in phosphorous can deplete calcium.
In addition, calcium absorption has long been thought to be stomach-acid dependent, but both stomach acid production and calcium absorption decline with age!
Bone-Up clinical trial
The results of a recent clinical trial published in the Journal of Nutritional & Environmental Medicine (Disilvestro RA et al. J Nutr Environ Med. 2007; 16(1):26-32) found that exercise and supplementation of calcium, vitamin D3 and other micronutrients from Bone-Up significantly improved bone health in young adult women.
In an 8-week double-blind placebo-controlled study of 24 female students ages 18 to 24, supplementation with Bone-Up (not placebo) was found to produce statistically signifi cant decreases in markers of bone degradation, while increasing levels of plasma bone specific alkaline phosphatase (an indicator of bone synthesis), plasma 2,5-OHvitamin D (an indicator of vitamin D nutritional status) and plasma parathyroid hormone.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
- books, probiotics and products bought in the SALE can NOT be returned
Can zinc deficiency cause depression?
The health benefits of zinc include a proper functioning of the immune and digestive systems, controlled diabetes, reduction in stress levels, improved metabolism, and an increased rate of healing for acne and wounds. Also, it is helpful in terms of pregnancy, hair care, eczema, weight loss, night blindness, cold, eye care, appetite loss, and many other conditions.
What is the importance of zinc?
Zinc plays a vital role in protein synthesis and helps regulate the cell production in the immune system of the human body. It is mostly found in the strongest muscles of the body and is found in especially high concentrations in the white and red blood cells, retina, skin, liver, kidneys, bones, and pancreas. The semen and the prostate gland in men also contain significant amounts of zinc.
In the human body, there are more than 300 different enzymes that require zinc to function normally. Researchers believe that 3,000 proteins (out of approximately 100,000) have this vital mineral.
A normal person has two to three grams of zinc at any given time. There are organs in the human body which secrete it, such as the salivary gland, the prostate gland, and the pancreas. Even cells involved in the activity of the immune system secrete zinc. It is used up in various metabolic processes and eliminated through normal excretory and urinary channels, so it needs to be replenished often. If it isn’t, you will begin to suffer from deficiency symptoms.
When you think about supplements, what are the first thoughts that go through your mind? Whey protein, nitric oxide, creatine, fat burners, or maybe something else? These are the ones that consume the ads.
What if I told you though that the most important supplement that you must have in your arsenal is not on this list? That is your basic multivitamin. From the chewable ones you took as a kid to the ones you have now. Oh, you don't take them? If not, you better change that immediately if you want to meet your fitness goals.
For the human body to complete all the tasks it has in a normal day, it must be given a wide and complex variety of vital nutrients. Becoming deficient in any one of these essential vitamins or minerals causes breakdown of the metabolic pathway that produces optimum efficiency and performance goes down quick. Obviously, this is NOT what you want!
Most supplements come with instructions to ingest them with a meal. This is in the assumption that meal contain fat, as fat will aid with absorption through the gut wall. Whether or not this can be your first meal of the day, depends on how much fat it contains. Especially fat-soluble vitamins, such as A,D, E and K need fat for proper absorption.
A work-around is to ingest them together with a larger amount of fish or krill oil softgels if your first meal doesn't contain enough fat.
Another reason take supplements with a meal, is that taking it by itself, can cause nausea or discomfort.
It's not only gelatine and biotin that make your nails stronger. Studies show that silicon compounds do so too. Belgian researchers demonstrated the effect of orthosilicic acid in an experiment in which they gave women with an aging skin a mere 10 mg silicon daily.
Osteoporosis is a naturally occurring phenomenon when bones decrease in density, resulting in weakness and a higher likelihood to break.
Anyone can develop osteoporosis, not just women over 50 years but also men (generally over 70) or anyone who's been bedridden for a long time. The scary part is that bone loss happens without noticable symptoms until a bone breaks spontaneously after a fall that normally would only leave bruises.
mix 1 scoop (6.6 g) with a large glass of cold water. For best absorption, take with food times per day or as directed by your qualified healthcare professional.
Each serving contains 50% of recommended daily intake for calcium.
Two servings per day provides 100% of average calcium requirement.
contains per daily serving (6.6g)
total carbohydrate 2g
Vitamin C (as calcium ascorbate) 100 mg (167% RDI)
vitamin D3 (cholecalciferol) 500 ie (125% outdated RDI)
vitamin K2(as natural MK 7, menaquinone-7) 23 mcg (29% RDI)
elemental calcium (from Microcrystalline Hydroxyapatite (MCHA) 500 mg (50 % RDI)
magnesium citrate 250 mg (63% RDI)
phosphorus (from Microcrystalline Hydroxyapatite (MCHA) 180mg (18% RDI)
zinc monomethionate (OptiZinc) 5 mg (33% RDI)
copper gluconate 0.5mg (25% RDI)
manganese citrate 0.5 mg (25% RDI)
potassium citrate 250mg (7% RDI)
sodium 25mg (1% RDI)
boron citrate 1.5 mg†
silicon (JarroSIl Activated Silicon , proprietary formula of molecular clusters of stabilized sicilic acid 10mg†
RDI = Recommended Daily Intake
† = RDI not established
active ingredients (microcrystalline hydroxyapatite, calcium, phosporus, magnesium, ascorbic acid, zinc, boron, copper, manganese, activated silicon, cholecalciferol, menaquinone), flavour (natural orange flavour, citric acid), filler (hydrolyzed bovine collagen, guar gum), sweetener (organic rebiana stevia extract), colour (beta carotene)
keep dry and closed at normal room temperature between 15 - 22°C.
keep out of reach of young children
contains traces of soy
contains no other familiar allergens (wheat, gluten, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)