D3 - cholecalciferol 5000iu 100 softgels - 125mcg | Jarrow Formulas
Jarrow Formulas Vitamin D3 5000iu (125mcg) with cholecalciferol is the most bioavailable form of vitamin D with a high potency and prolonged retention time. It is required for enhanced absorption and proper blood levels of calcium and phosphorous, promoting the health of bones, muscles, and other organs
who benefits from vitamin D3?
The World Health Organization (WHO) recommends a daily intake of 1000 iu or more for good health. The ones to benefit from this advice are typically men and women who have office jobs, men and women over 40, men and women with a darker skin of African Arabian or African descent, men and women with skin disorders caused by vitamin D deficiency. Optimal vitamin D levels are a must for a beautiful elastic skin, a good prostate function and strong and healthy bone structure. A low vitamin D status has also been linked to low testosterone levels and vice versa.
what distinguishes Vitamin D3?
• vitamin D3 (cholecalciferol) softgels
• low levels linked to poor heart health
• free of vitamin A
• important for bone health: osteocalcin synthesis & calcium absorption
how does the active ingredient function in this product?
Fat-soluble Vitamin D3 is converted by the kidneys into the hormone calcitriol, the active form of Vitamin D3, which affects a variety of target tissues, including bone, intestine, muscle, brain, skin and immune cells. Calcitriol enhances calcium and phosphorous absorption and stimulates the synthesis of osteocalcin, an important structural protein in bone. Also, calcitriol is involved in proper cell differentiation (changing of cell function), including in prostate cells.
Vitamin D is a fat soluble vitamin that is obtained from food, sun exposure, and dietary supplements. Once vitamin D is ingested or synthesized in the skin, it undergoes two hydroxylation reactions in the body, first in the liver to calcidiol (25-hydroxycholecalciferol), and then in the kidney to calcitriol (1, 25-dihydroxycholecalciferol).
Vitamin D is critical for healthy bone development, remodeling and maintenance. It is also known to play a key roll in the maintenance of many other organ functions.
Why vitamin D3?
Two forms of vitamin D, vitamin D2 (ergocalciferol) and D3 (cholecalciferol), are available in supplements and fortified foods. Although both forms can raise available vitamin D in the body, vitamin D3 produces three times the amount of available vitamin D metabolites with a longer retention time and higher activity potential.
Jarrow Formulas Vitamin D3 utilizes only cholecalciferol, the superior kind of vitamin D, to ensure the delivery of a high quality, more bioavailable form of vitamin D.
Vitamin D deficiency in the U.S.
Obtaining sufficient vitamin D from food and daily sun exposure can be difficult for many people. The US National Health and Nutrition Examination Surveys (NHANES) have reported that the average intake of vitamin D has been declining and that many children and adults in the United States are likely to be vitamin D deficient. This trend may be due to increased body mass index (BMI), reduced dairy consumption, lactose intolerance, milk allergy, increased use of sun protection, and vegetarianism.
In breast-fed infants, human milk alone is not sufficient to provide the required amount of vitamin D. The American Academy of Pediatrics (AAP) recommends vitamin D supplementation in both infants and mothers. Women and older individuals also tend to have vitamin D levels that are lower than recommended levels. In the population above age 50 in particular, this may be caused by a slowed or compromised metabolism and poor absorption of vitamin D.
Adequate vitamin D is essential for optimal health. Supplementation of vitamin D with Jarrow Formulas Vitamin D3 can contribute to the required daily vitamin D intake and thus promote healthy bones, skeletons, immune function, and cell protection in both the young and the old.
Vitamin D plays an important role in stimulating the absorption and maintenance of proper blood levels of calcium and phosphorous, critical minerals for bone development and preservation. Numerous studies have shown that vitamin D3 supplementation may support bone strength and reduce the risk of falls, fractures, and bone loss in elderly individuals, especially those with inadequate calcium and/or vitamin D intakes, postmenopausal conditions, and difficulty exercising. Vitamin D3 supplementation can support not only healthy bone development and growth in young children and adults, but also promote balanced remodeling and rebuilding of bones in a mature population
Cell growth and differentiation
Although a precise mechanism has not been elucidated, vitamin D has been shown to support balanced cellular growth and differentiation.
Vitamin D has an ability to modulate production and stability of proteins and associated factors that are critical for healthy cell proliferation, apoptosis, and differentiation. Additional pre-clinical and clinical studies are underway to discover further benefi ts of vitamin D in sustaining well-controlled cell function and growth.
Vitamin D has been shown to regulate both immune-promoting and immune-suppressing effects of immune cells and factors. Interactions among vitamin D receptors and other molecules on the immune cells enhance the communication between various signaling pathways, resulting in efficient and appropriate immune responses. In addition, this basic vitamin may play a signifi cant role in cardiovascular health by regulating blood pressure (through balanced hormone secretion), heart and vessel muscle function, and normal immune response. A growing body of research on vitamin D also suggestes benefits of this vitamin to normal mood and blood sugar regulation, and overall mortality and well-being, although additional studies are necessary for better understanding of the modes of action.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
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Pigmentation spots : why do we get them when we age?Do you sometimes look down onto your arms and notice they are covered with white spots that resemble freckles in reverse?
Especially when arms get tanned in summer, these white spots tend to stand out more than ever.
This led me to the idea to look up what can be a cause of this weird pigmentation.
Mine turns out to be one called idiopathic guttate hypomelanosis (IGH), in other words, an unexplained teardrop-shaped lack of pigmentation, which is apparently very common among most people of over 40 years , but may also happen at a younger age. These white spots appear on the shins, legs, arms, and other sun-exposed areas of the body like the face, neck, and shoulders.
Apparently the body experiences a gradual reduction of melanoyctes and skin cells no longer produce pigment, a similar process that causes the graying of hair. The condition is also increasingly being seen in both sexes and darker skinned individuals with a history of long-term sun exposure, which has lead scientists to believe that excessive sun exposure and sun damage is another cause of these white spots.
They are generally 1 to 3 mm in size and commonly show up on the legs before progressing to other parts of the body.
These white spots are not caused by trauma or infection, nor do they indicate an increased risk of skin cancer.
Hereditary factors may be involved because this skin problem seems to run in families.
IGH is not related to vitiligo, in which melanin-producing cells called melanocytes die or are unable to function properly and no longer form melanin.
Other common causes of skin discolorations are
take 1 softgel capsule with water or an acidic fruit juice once a day with a meal or as directed by a qualified medical physician or pharmacist
always consult you physician when undertaking a supplement program to verify if your medication interferes with this supplement.
contains per daily serving (1 softgel capsule)
vitamin D3 (cholecalciferol, 125µg) 5000 iu (630% RDI)†
iu = international units
† the Recommended Daily Intake
To prevent chronic deficiency an intake of 400iu is recommended, while optimal intake for adults is somewhere between 1000 and 2500 iu/day.
Take a lower amount in summer, when you get into the sun often or when you have a fair skin type.
Take a higher amount in winter, when you spend most of your time indoor or when you have a dark skin type.
active ingredient (cholecalciferol,D3), filler (extra virgin olive oil), capsule (bovine gelatin, glycerin and water)
keep dry and closed at normal room temperature between 15 - 22°C.
keep out of reach of young children
If you have a medical condition (especially kidney stones or dysfunction, hyperparathyroidism, hypercalcemia, lymphoma, or sarcoidosis), are pregnant, lactating, trying to conceive, under the age of 18, or taking medications, consult your healthcare professional before using this product.
Vitamin D can interact with drugs like Xenical®, antacids with an aluminum component (ask your pharmacist) or when you are medication against Lupus
contains no familiar allergens (wheat, gluten, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish, shellfish or mollusks)