Green Lipped mussel 60 softgels - omega 3 free fatty acids | AOR
AOR Green Lipped FFA is the stable free fatty acid extract of Perna canaliculus, the New Zealand green-lipped mussel. This extract contains an unique profile of fatty acids not found in significant amounts in standard fish oil supplements. These fatty acids modulate the body's production of eicosanoids, key local cellular "hormones" involved in inflammatory responses, acting through inhibition of 5- and 12-lypoxygenase and other key enzymes. Studies show that these effects make this mixture more effective nutritional support than conventional fish oils.
• unique omega-3 alternative to fish oil
• powerful anti-inflammatory action
• improves symptoms of arthritis
• blocks the production of pro-inflammatory signals
A Unique Extract
Green Lipped FFA is an extract of the green-lipped mussel, which contains rare forms of omega-3 fatty acids. These omega-3’s, eicosatetraenoic acid (ETA) and its precursor stearidonic acid (SDA), are not found in significant amounts in standard fish oils, and are potent antiinflammatory agents.
AOR’s green-lipped mussel extract is a stable fatty acid extract, which is a far more superior and effective extract compared to other green-lipped mussel extracts available on the market.
Stops Inflammation in its Tracks
ETA and SDA have been found to improve stiffness and joint functionality and decrease night pain in patients with rheumatoid and osteoarthritis. They also have benefits in bronchial asthma and premenstrual syndrome. ETA and SDA work their magic by modulating the body’s production of inflammatory signaling molecules called eicosanoids. Some eicosanoids block inflammation, but others act as harmful pro-inflammatory signals. If the normal pathway of pro-inflammatory eicosanoids is blocked, they can be produced by an even more destructive pathway. Many antiinflammatory agents only block the first pathway, but ETA and SDA block both routes of production. This is particularly important in autoimmune disorders.
Besides the anti-inflammatory mechanisms common to all omega- 3s, ETA and SDA have unique and potent actions. Green Lipped FFA protects against the damage and pain of inflammation in ways that other supplements cannot match.
Inhibiting COX and LOX Alike
Omega-3 fatty acids are now well-known inflammation fighters. Both omega-3 fatty acids, and nearly all antiinflammatory drugs, work by affecting a group of local, cellular “hormones” called eicosanoids. Eicosanoids are messengers that cells use to communicate with one another. Some (“bad”) eicosanoids promote inflammation, while other (“good”) eicosanoids have potent anti-inflammatory functions. “Bad” eicosanoids are made from an omega-6 fatty acid called arachidonic acid. Most drug approaches to inflammation work by inhibiting the formation of the series-2 prostanoid group of “bad” eicosanoids. Prostanoids are formed from arachidonic acid by an enzyme called cyclooxygenase, or COX.
But while these drugs certainly provide symptomatic relief in the short term, COX-2 inhibitors can actually accelerate the underlying inflammatory disease in the long term, by diverting arachidonic acid into another, slower-acting, and ultimately more destructive pathway: the lipoxygenase (LOX) enzyme pathway, which produces the ravaging series-4 leukotrienes. Leukotrienes are responsible for the long-term consequences of inflammation, which can result when a deranged immune system attacks the very body that it was designed to defend.
Therefore, blocking the COX pathway alone results in an imbalance – an imbalance that ultimately trades short-term gain for long-term pain. What people suffering with autoimmune disorders most need is a “dual pathway inhibitor:” a molecule which will shut down COX-2 and LOX alike, preventing the formation of all “bad” eicosanoids.
Introducing ETA and SDA
Eicosatetraenoic acid (ETA) and its precursor stearidonic acid (SDA), are very rare in the normal Western diet, but are found in significant amounts in the fatty acids of the green-lipped mussel (Perna canaliculus). Studies have confirmed that the anti-inflammatory properties of the green-lipped mussel are due to their content of SDA and ETA.
ETA and SDA Top the Omega-3s
Animal studies have clearly shown that the ETA- and SDA-rich fatty acid extract of P. canaliculus is far superior to other omega-3 sources at quenching the fires of inflammation, giving more potent anti-inflammatory benefits at significantly lower doses.
In a new randomized, double-blind, controlled trial involving rheumatoid and osteoarthritis sufferers, significant improvements were reported in morning stiffness and measures of joint functionality during the double-blinded phase among rheumatoid arthritis sufferers taking the SDA/ETA-rich oil. Furthermore, night pain was “much improved” in 40% of subjects, and vanished in an additional 26.7%. Assessment by doctors and patients concluded that 73% of the persons with rheumatoid arthritis had experienced a good response – including 20% who became completely symptom-free by the end of the double-blind phase. The results were similar in the osteoarthritis patients.
Similar results have been reported in an unpublished pilot trial and in case reports. A double-blind, placebo-controlled trial vouches for the benefits of an SDA- and ETA-rich fatty acid supplement in bronchial asthma, and testimonial accounts and animal studies suggest benefits for premenstrual syndrome as well.
How Does It Work
The anti-inflammatory powers of all omega-3 fatty acids are grounded in biochemistry: the omega-3s’ ability to bind up key enzymes involved in making “bad” eicosanoids. And as studies show, ETA and SDA more potently prevent the formation of both types of “bad” eicosanoids: series-2 prostanoids and series-4 leukotrienes. Mechanisms are believed to include:
•A stronger ability to tie up delta-5 desaturase, the enzyme that forms arachidonic acid
•Indirectly increasing the production of the “good” eicosanoids from DGLA
•ETA’s close chemical resemblance to arachidonic acid, leading to stronger tying up of the LOX enzyme
•ETA and SDA bind up COX-2, and also work at the gene level to reduce the production of COX-2 from the DNA code
ETA/SDA-based omega-3 supplements are an orthomolecular revolution, providing powerful support against inflammation in ways that other natural supplements can’t match.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
- available by mid-August
- €0 (NL) - €7,50 (BE/DE) - €9+ (EU)
- free shipping above €30 (NL) - €60 (BE/DE) or €6 discount above €75 (EU)
- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
- books, probiotics and products bought in the SALE can NOT be returned
Take 2 softgels twice daily for the first 2 months, followed by one softgel twice daily for the next 4 months, taken with a fat-containing meal, or as directed by a qualified health care practitioner.
contains per daily serving (1 softgel)
Green-lipped mussel stable fatty acid extract 50mg
active ingredients (Green-lipped mussel stable fatty acid extract (mollusks)), fillers (olive oil), antioxidant (d-alpha tocopherol), softgel capsule (gelatin, sorbitol, glycerin)
keep dry and closed at normal room temperature between 15 - 22°C.
keep out of reach of young children
Do not use if pregnant or breastfeeding
derived from mussels
contains no other familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, or fish)