HCActive Garcinia Cambogia 90 capsules - hydroxycitric acid | Jarrow Formulas
Jarrow Formulas HCActive Garcinia Cambogia is a 70% concentrate of hydroxycitric acid (HCA) stabilized as a potassium-magnesium salt extracted from the fruit of Garcinia cambogia.
HCActive™ was tested at Georgetown University and found to be highly absorbed and more bioavailable than a leading HCA potassium-calcium salt.
HCActive™ supports appetite control and weight management.
HCActive™ improves antioxidant status and mitochondrial function plus reduces inflammation in fat cells. Chronic dysfunction of mitochondria, oxidative stress, and inflammation all contribute to fat cell & tissue dysfunction, which promotes metabolic diseases (e.g., metabolic/insulin-resistance syndrome, type 2 diabetes). Nutritional therapies are aimed at correcting such metabolic aberrations and HCA packs a mean punch in the fight against metabolic dysfunction.
HCA is popular as a weight loss aid, but apparently does much more in the body, including protecting the mitochondria (the “energy factories” of the cells). The role of mitochondria in metabolic dysfunction and disease is an active area of research. Increased cellular generation of reactive oxygen species (ROS) damages the mitochondria, causes injury to the cell and promotes the production of pro-inflammatory mediators as well as further ROS.
Inflammation is linked to the metabolic syndrome at the cellular level by way of damage to the antioxidant-defense enzyme system and mitochondria. This damage, in turn, propagates further production of pro-inflammatory mediators.
To uncover cellular mechanisms involved, researchers examined adipocytes (fat cells) and one of their important internal structures, the endoplasmic reticulum (ER). ER stress contributes to cell/tissue and metabolic dysfunction by disturbing the normal synthesis, secretion and folding of proteins leading to increased ROS production and inflammation. Increased ROS and diminished antioxidant defenses cause chronic cell injury. HCA protected fat cells from ER stress by improving the antioxidant status to reduce ROS and improve the function of the mitochondria to short circuit the ER stress–inflammation loop in these cells.
The Metabolic syndrome is taken as being largely synonymous with insulin resistance and involves multiple metabolic perturbations: elevated fasting blood glucose levels, central obesity, elevated blood triglycerides, reduced high-density lipoprotein (HDL) cholesterol ("good" cholesterol), elevated blood pressure and, more recently, inflammation. Weight gain is another common symptom.
One hypothesis is that a well-recognized increased consumption of sugars and refined carbohydrates plays a pivotal role in the increase of these unwanted outcomes. Suitable life-style changes should be both preventative and to some extent corrective of the metabolic syndrome. However, dietary restrictions and regular engagement in exercise are not easy alternatives for many people. Hence, it is important to find and explore therapeutic nutritional alternatives.
HCA, which can be obtained from a variety of Garcinia species, has been tested primarily as a weight loss compound. As is true of many herbal extracts, studies have shown vast differences in efficacy depending on extraction methods, purity and other factors.
Recently, attention has turned to other possible benefits with a number of animal trials demonstrating reductions in various components related to inflammation as well as improved insulin sensitivity and reductions in other aspects of the metabolic syndrome. However, until recently no clear mechanism of action involving inflammation had been uncovered. The finding that HCA reduces ER stress helps to explain many otherwise puzzling benefits of HCA and suggests that HCA might play an important part in combatting the metabolic syndrome by interrupting the vicious cycle of an ER stress–inflammation loop (reinforcing each other).
HCActive™ is protected by 9 U.S. patents and a trademark belonging to to Glykon Technologies Group, LLC.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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- <€30: €4 (NL) - €7 (BE/DE) - €9+ (EU)
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- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
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Take 3 capsules twice per day 30 to 60 minutes before breakfast or lunch and again 30 to 60 minutes before supper, or as directed by your qualified healthcare professional.
contains per daily serving (3 capsules)
HCActive potassium-magnesium hydroxycitrate 1500mg †
(Garcinia cambogia extract as fruit w 70% hydroxycitric acid, 1050 mg)
† = Recommended Daily Intake not established
active ingredient (HCActive potassium-magnesium hydroxycitrate), filler (cellulose, stearic acid triglyceride (vegetable source)) , anti-coagulant (silicon dioxide), filler (magnesium stearate (vegetable source)), veggie-capsule (hydroxypropylmethylcellulose)
keep dry and closed in a cool place, but do NOT refrigerate.
keep out of reach of young children
Do not use this product if you have a medical condition (especially impaired kidney function, diabetes and/or glucose control).
NOTE: Women who are pregnant, lactating, trying to conceive, persons under the age of 18, or taking medications, consult your healthcare professional before using this product.
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)