Milk Thistle Silymarin 80% 200 capsules - Silybum marianum | Jarrow Formulas
Jarrow Formulas Milk Thistle (Silybum marianum) 30:1 concentrate is standardized to contain 80% total Milk Thistle seed flavonoids, including the important Silymarin fractions isosilybinins A and B, silybinins A and B, silychristin and silydianin.
This particular group of flavonoids, collectively known as Silymarin, supports liver function by raising protective glutathione levels.
who can benefit from Milk Thistle?
Milk thistle is recommended for people concerned about liver health. It protects against toxins (e.g., alcohol, second-hand smoke, air pollution, pesticides, heavy metals, recreational and anabolic drugs, and various prescription medications). It is an important addition to detoxification regimens and an excellent tonic for anyone under stress. Its ability to increase bile flow makes it effective as a mild laxative and important in managing cholesterol.
• supplies a standardized 30:1 extract yielding 80% silymarin
• boosts immune response in clinical trials
• demonstrates liver-protecting benefits in human studies
• possesses antioxidant and free radical scavenging activity
• improves glutathione levels, the body’s major antioxidant
• stimulates liver protein synthesis and liver cell regeneration
An Ancient Herb
The Greek herbalist Dioscorides catalogued milk thistle in his list of healing plants for liver ailments, improving bile flow and stimulating digestion. The Roman author Pliny was of a similar opinion.
Indeed, milk thistle (Silybum marianum) extracts have been used as traditional herbal remedies for almost 2000 years and milk thistle is now extensively cultivated as a healing herb. This is especially true in Germany, where milk thistle is quite popular. Despite its distinctive prickly leaves and milky sap, milk thistle is sometimes confused with a different plant known as blessed or holy thistle (Cnicus benedictus).
Today, milk thistle extracts are among the most popular and the best researched of all herbal remedies. Yet, this herb had largely become forgotten by the mid-20th century. It was barely mentioned in the United States Dispensatory of 1947, and the most common folk use outside of Central Europe was to improve lactation.
Modern research has focused on bile disorders and liver dysfunction. German scientists have produced an extract called silymarin, which has a variety of liver-protectant properties. The active principles normally constitute only 1-4% of the total plant, so it is necessary to concentrate the extract extensively to provide benefits. Jarrow Formulas Milk Thistle provides just such a potent concentrate.
Special antioxidant benefits
Silymarin refers to three active flavonoid components of milk thistle: primarily silybin with smaller amounts of silydianin and silychristin.
This trio neutralizes toxins and helps regenerate damaged livers to improve liver function. Its action rests primarily upon the ability to inhibit production and activity of hepatotoxic (liver toxic) compounds.* More recent evidence indicates that it benefi ts the health of several other organs as well.
The liver is the primary organ for detoxification. Many toxins are either free radicals, or encourage free radical production and may interfere with the liver’s defenses against free radicals. As a potent antioxidant, silymarin intervenes in free radical generation and protects against many reactive oxygen species. In some measurement systems, silymarin is ten times more effective than vitamin E in preventing unwanted oxidation. The extract also increases the liver’s content of the antioxidant enzyme glutathione (GSH) by ~35%, and increases the levels of the body’s major antioxidant enzyme, superoxide dismutase (SOD).
Silymarin also inhibits the actions of lipoxygenase in the liver. Lipoxygenase acts upon polyunsaturated fatty acids to produce pro-inflammatory compounds called leukotrienes, which cause damage to liver cell membranes.
Silymarin is active against all of these assaults upon liver cell integrity and function. It therefore has direct and indirect antioxidant benefits by elevating the body’s own defenses. Research has shown that milk thistle extracts also significantly enhance immune function and cellular immune biomarkers.
Supporting liver regeneration, bile solubility
The liver is capable of extensive self-regeneration, but silymarin can even markedly increase this ability to replace damaged cells.
There is also some suggestion that silymarin stimulates protein synthesis in the liver. Nevertheless, silymarin does not encourage malignant liver cell growth.
Growing evidence suggests that silymarin has protective properties to the kidneys that mirror those in the liver.
Classically, milk thistle is associated with improved digestion and bile production. These are important functions of the liver and their impairment can lead to disease. Clinical trials have supported this traditional employment of the herb. The extract can increase bile solubility and possibly reduce the probability of stone formation.
Silymarin exhibits poor solubility in water. Delivery in the form of teas provides less than 10% of total activity. Older studies demonstrating silymarin as a bile fl ow-inducer used alcoholic tinctures rather than the water-based preparations commonly sold today.
Only 20-50% of silymarin is assimilated from the gastrointestinal tract at any given time. Thus, an effective milk thistle supplement needs to be highly concentrated, like Jarrow Formulas Milk Thistle to provide a physiologically significant amount. According to the German monograph covering milk thistle, 12-15 grams of the crude herbal extract provides 200-400 mg silymarin. This is equivalent to the amount delivered by only 3 capsules of Jarrow Formulas Milk Thistle.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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How to cure a hangover
Quite a lot of people wake up the day after a major holiday like the recent King's Day or Liberation Day with a hangover due to imbibing too much alcohol.
The most widespread assumption is that a hangover is caused by not drinking enough water, and therefore those that aren't drunk enough to remember what to do, will drink a few litres of water before going to bed or at least will try to do so the next morning. Other very popular cures are to drink a lot of coffee and eat a hearty egg-based breakfast. Another advice was heard on the radio from a Dutch food blogger who exclaimed how eating toast with honey is a definite cure for hangovers. Around the world a myriad of folk remedies exist for this ancient 'disease'.
Do these remedies actually work and are there some others you didn't think of?
Before we dive into that, let's first discuss the hangover itself.
When is drinking alcohol bad for your health?In the past decade we were told indulging in one or two glasses of alcohol (just one for women) a day is healthy. This was even one of the many recommendations in the national (Dutch) health guidelines. In the past year though, a drastic change occurred: the recommendation changed into zero to perhaps to a most one glass of alcohol a day! So, what gives?
Take 1 to 3 capsules per day, or as directed by your qualified health care consultant.
contains per daily serving (1 capsule)
milk thistle seed 30:1 extract 150 mg †
from Silybum marianum 80% total flavonoids
† = Recommended Daily Intake not established
active ingredient (milk thistle (Silybum marianum)), filler (cellulose, vegetable magnesium stearate) , anti-coagulant (silicon dioxide), capsule (hydroxypropylmethylcellulose)
keep dry and closed at normal room temperature between 15 - 22°C.
keep out of reach of young children
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)
suitable for vegetarians and vegans