Ortho Sleep 60 capsules - GABA, theanine, 5HTP, melatonin, valerian root, passionflower and lemon balm | AOR

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Ortho Sleep 60 caps - GABA, theanine, 5HTP, melatonin, valerian root, passionflower and lemon balm | AOR

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Retail price: 47,00
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brand:Advanced Orthomolecular Research
best before:May 2020
appearance:v-capsules
diet:vegan, hypo-allergenic
details:12+ items = -25%
availability:in stock
shipping costs:€30+: €0 (NL) - €2+ (EU)
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AOR's Ortho Sleep was formulated to be the most comprehensively powerful natural sleep-aid available to improve overall sleep.
Ortho·Sleep is clinically proven to help increase the total sleep time (aspect of sleep quality) in people suffering from sleep restriction or altered sleep schedule such as shift-work and jet lag, and helps relieve the daytime fatigue associated with jet lag.
Ortho·Sleep™ is also clinically proven to help reduce the time it takes to fall asleep (sleep onset latency aspect of sleep quality) in people with delayed sleep phase syndrome, and helps to re-set the body's sleep-wake cycle (an aspect of the circadian rhythm).

• prevents insomnia
• restores restful sleep patterns
• protects blood vessels from damages
• promotes relaxation and reduces anxiety

AOR's Ortho Sleep was the Gold Winner of the Alive Awards 2012 for best herbal product!

background reading
Insomnia – a Common Problem
Sleep is essential for maintaining proper cognitive and motor function, however up to 58% of Americans suffer from symptoms of insomnia, a sleep disorder characterized by difficulty falling asleep and staying asleep. This results in disrupted sleep patterns that can negatively influence many aspects of life, including reduced performance at work or school and moodiness.

Neurotransmitters and Sleep
Neurotransmitters are chemical messengers that transmit messages between nerve cells in the brain. These important messengers are essential for regulating many processes and responses in the body, including day-night cycles and sleep. Some of the most important of these neurotransmitters are GABA, which reduces anxiety and promotes relaxation, as well as serotonin and melatonin which help regulate the body’s daily sleep cycle.

Getting More Sleep
Ortho-Sleep contains a carefully formulated blend of nutrients and compounds that have been shown to be effective in combating insomnia and promoting healthy, restful sleep. These include neurotransmitters like GABA and melatonin, as well as 5-HTP, a serotonin precursor. The formula further includes the amino acid L-theanine as well as valerian root, passionflower extract, and lemon balm, all of which possess relaxing properties, and work to increase the activity of GABA in the brain.

The Importance of Sleep
Sleep is a natural state of bodily rest that is essential for the maintenance of normal motor and cognitive function as well as general alertness and well being. Sleep is regulated by the body’s internal clock, which keeps track of light levels, the time of day and other important cues for sleep and awakening. There are two primary types of sleep, REM (Rapid Eye Movement) sleep, which is dreaming sleep, and Non-REM sleep, which consists of four stages of progressively deeper sleep. All sleep stages are important, however, deep sleep and REM sleep are especially vital.

Many people have trouble sleeping or have disrupted sleep patterns. People suffering from insomnia spend less time in deeper levels of sleep, wake up more often, and experience a reduction in very important REM sleep. Chronic insomnia can lead to excessive sleepiness during the day, impaired cognitive and motor function, confusion, irritability, an increased risk of injury, and an overall reduced quality of life. Insomnia can be caused by a variety of factors, including stress, anxiety, diet, or a disruption of the body’s internal clock (jet lag).

Natural Relief from Sleeplessness
Neurotransmitters are the key to sleep regulation. These chemicals are like tiny messengers in the brain, transmitting signals from one neuron to another and modulating a huge number of functions in the human body, including sleep.
Gamma-aminobutyric acid or GABA is the most important inhibitory neurotransmitter in the brain. GABA acts like a “brake” during times of stress or anxiety, regulating brain excitability and inducing relaxation. GABA receptors are highly concentrated in the hypothalamus, the region of the brain associated with sleep. GABA is effective against insomnia, and has been shown to affect the brain directly, increasing ?-brain waves (those associated with relaxation) and reducing ?-brain waves (those associated with anxiety and stress).

Serotonin and melatonin are also key neurotransmitters. Melatonin is produced by the pineal gland in the brain, and it controls the body’s internal clock. Melatonin has been shown to increase sleep time and reduce the time it takes to fall asleep. It can also help to reset the body’s sleep-wake cycle, a benefit to those suffering from jet lag. Serotonin is essential for sleep modulation in its own right, and can also be converted by the body into melatonin.
5-HTP is a metabolite of the amino acid tryptophan and a precursor to serotonin. 5-HTP boosts serotonin levels, and can also increase REM and deep sleep phases, making sleep more restful.

L-theanine, valerian root, passionflower extract and lemon balm are four other nutrients that have demonstrated promising effects in promoting restful sleep.
L-theanine, an amino acid from green tea, is known for its relaxing and anti-anxiety properties. It can act directly on the brain, influencing brain wave patterns in a similar fashion to GABA, and also indirectly by stimulating GABA production.
Valerian root and passionflower extract have long been recognized as effective sleep aids, helping to reduce restlessness and anxiety. There is evidence that compounds in these plants are able to stimulate increased GABA release or activate GABA receptors, as well as inhibit enzymes that break down neurotransmitters like GABA and serotonin.
Lemon balm has also been shown by research to be an effective sleep aid, especially when used in combination with other herbal extracts like valerian root.

code MPN:
AOR04186
brand :
Advanced Orthomolecular Research
best before:
May 2020
appearance:
  • v-capsules
audience :
  • adults
  • travellers
diet:
  • vegan
  • hypo-allergenic
details:
  • 12+ items = -25%
quantity discount:
  • any 2+ = -5%!
  • any 3+ = -7.5%!
  • any 4+ = -10%!
  • any 5+ = -12.5%!
  • any 6+ = -15%!
  • any 8+ = -20%!
  • any 12+ = -25%!
availability:
  • in stock
shipping costs:
  • €30+: €0 (NL) - €2+ (EU)
information:
  • quantity discount is valid for any combination of products
  • free shipping above €30 (NL) - €50 (BE/DE) or €7 discount above €50 (EU)
  • keep out of reach of young children
  • a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
  • if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
  • books, probiotics and products bought in the SALE can NOT be returned

Can you ever get used to working night shifts?

Last Sunday the Daylight Saving Time ended, and if your reaction was similar to mine, it felt like we plunged right into the darkest time of year. Only a few days earlier, I'd be out and about in broad daylight to get your parcels delivered to you on time, then all of a sudden dusk had set in already.
Maybe your reaction was similar, or if you are someone who rises early, you're happy to see the sun back for a short while when waking up.

Or, perhaps you aren't seeing the sun much at all, because you belong to the almost 20% of people who habitually work at weird hours. Some of you may only work night shifts, while others will have rotating shifts.

For those of you, who may for one reason or another will have to work in shifts soon, we have gathered more background information on how shift work affects your life and how to adapt to it.
Almost everyone has hard time adapting to night shifts, but most people can adapt to it within a few months.

Misconceptions about drug abuse

"Did you hear the news already? Rich Piana died last week!" exclaimed a good friend of ours. "Rich who??" was my response. Then it dawned on me he was speaking of the same person about whom I had been reading the other day and of which I only remembered his face and enormous physique.
Rich Piana, who had a large group of followers on Youtube and Instagram, as he had a most bizarre amount of muscles and was famous for his grueling workouts. 
Almost immediately everyone assumed he probably died due to overuse of steroids and associated muscle-building products.
It is not so weird to assume this as the amount of bodybuilders, who haven't lived past 50 years is staggering, because of the ever more dangerous means of attaining a muscular physique that is bigger than that of other competitors in bodybuilding demand more lives every decade.
The burning desire to create even more muscle mass wins from common sense. When discussing his death people referred a very good documentary called:Bigger, Stronger and Faster. Yet, at a lower level, the sports of recreational bodybuilders, apparently is one of the safest sports around.

How to deal with sleeplessness

Sleep problems are as old as mankind, but it has become more problematic than ever with the advent of modern technology resulting in "poor sleep hygiene". Exposure to bright light late at night results in falling asleep too late and sleeping too little, because it disturbs the body clock that is regulated by melatonin.

recommended use
Take 1-2 capsules before bedtime or as directed by a qualified health care practitioner.

contains per daily serving (2 capsules)
lemon balm extract (Aerial Parts)† 300 mg
L-theanine 200 mg
valerian Root extract (0.8% Valerenic acid) 150 mg
GABA (Gamma Aminobutyric Acid) 100 mg
L-5-Hydroxytryptophan (Griffonia Seed) 100 mg
passionflower extract (3.5% Vitexin) 32 mg
melatonin 3 mg

ingredients
active ingredients (alemon balm extract, L-theanine, valerian root extract, GABA, L-5-hydroxytryptophan, passionflower extract, melatonin), filler (microcrystalline cellulose, maltodextrin, Arabic gum), anticoagulant (silicondioxide), capsule (hypromellose)

storage
keep dry and closed at normal room temperature between 15 - 22°C.
keep out of reach of young children

warning and contra-indication
Do not take if pregnant, nursing or trying to conceive
Consult a health care practitioner prior to use if taking carbidopa or drugs/supplements with serotonergic activity. These may include, but are not limited to, L-tryptophan, S-adenosylmethionine (SAMe), St. John's Wort, antidepressants, pain killers, cough/cold medication containing dextromethorphan, anti-nausea, anti-blood pressure and anti-migraine medication.
Discontinue use and consult a health care practitioner if you show signs of weakness, oral ulcers, or abdominal pain accompanied by severe muscle pain or if you experience skin changes.
Some people may experience gastrointestinal disturbances such as diarrhea, nausea, vomiting and abdominal pain as well as drowsiness. Do not use if you have scleroderma. Hypersensitivity (e.g. allergy) has been known to occur; in which case, discontinue use.
Do not drive or use machinery for 5 hours after taking Ortho·Sleep. Exercise caution if engaging in activities requiring mental alertness.
Do not take Ortho·Sleep if you are taking immunosuppressive drugs.
Not to be used by individuals under the age of 18 or those with a medical condition such as a hormonal disorder, diabetes, liver or kidney disease, cerebral palsy, seizure disorders, migraine, depression and or hypertension.
Consult a health care practitioner if sleeplessness persists continuously for more than 3 weeks (chronic insomnia). Consult a health care practitioner if symptoms persist or worsen.
Consumption with alcohol, other medications or health products with sedative properties is not recommended.

allergy information
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)

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